TARGET-MPN aims to define molecular mechanisms of disease persistence and progression in myeloproliferative neoplasms (MPN). To achieve this goal, investigators from distinct sites with unique expertise regarding different aspects of molecular genetics, persistence, progression and therapeutic induction of disease regression in MPNs joined forces.

The consortium aims to identify and functionally characterize novel molecular targets in order to develope individualized therapies to eradicate persistent MPN cells and to prevent disease progression.